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[4] Blood that gathers in the brain after an injury may damage brain tissue and thereby cause epilepsy. [8] Products that result from the breakdown of hemoglobin from blood may be toxic to brain tissue. [8] The "iron hypothesis" holds that PTE is due to damage by oxygen free radicals, the formation of which is catalyzed by iron from blood. [19]
Pentobarbital can reduce intracranial pressure in Reye's syndrome, treat traumatic brain injury and induce coma in cerebral ischemia patients. [8] Pentobarbital-induced coma has been advocated in patients with acute liver failure refractory to mannitol. [9] Pentobarbital is also used as a veterinary anesthetic agent. [10]
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.
Post-traumatic seizures (PTS) are seizures that result from traumatic brain injury (TBI), brain damage caused by physical trauma.PTS may be a risk factor for post-traumatic epilepsy (PTE), but a person having a seizure or seizures due to traumatic brain injury does not necessarily have PTE, which is a form of epilepsy, a chronic condition in which seizures occur repeatedly.
This route of administration is often used to bypass the blood-brain barrier because it can prevent important medications from reaching the central nervous system. This injection method is widely used in diseased mice models to study the effect of drugs, plasmid DNA, and viral vectors on the central nervous system.
Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [2] [3] and borderline personality disorder, [4] since many seem to act as mood stabilizers, and for the treatment of neuropathic pain. [5] Anticonvulsants suppress the excessive rapid firing of neurons during seizures. [6]
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Other intravenous anesthetic drugs such as midazolam or propofol may be used. [1] [2] Drug-induced comas are used to protect the brain during major neurosurgery, as a last line of treatment in certain cases of status epilepticus that have not responded to other treatments, [2] and in refractory intracranial hypertension following traumatic ...