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  2. Merck's Keytruda sets new 5-year survival standard for ... - AOL

    www.aol.com/news/mercks-keytruda-sets-5-survival...

    Keytruda competes with rival drugs from Bristol-Myers Squibb , Roche and others in several types of cancer. Merck's Keytruda sets new 5-year survival standard for advanced lung cancer Skip to main ...

  3. Pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Pembrolizumab

    Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody, more specifically a PD-1 inhibitor, used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, stomach cancer, cervical cancer, and certain types of breast cancer. [12] [14] [15] [16] It is administered by slow intravenous ...

  4. Merck's Keytruda Shows Improved Metastasis-Free Survival In ...

    www.aol.com/news/mercks-keytruda-shows-improved...

    Merck & Co Inc (NYSE: MRK) announced data from Phase 3 KEYNOTE-716 trial of Keytruda (pembrolizumab) as adjuvant treatment for patients with resected stage IIB and IIC melanoma. The trial has met ...

  5. Progression-free survival - Wikipedia

    en.wikipedia.org/wiki/Progression-free_survival

    Progression-free survival (PFS) is "the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse". [1] In oncology , PFS usually refers to situations in which a tumor is present, as demonstrated by laboratory testing, radiologic testing, or clinically.

  6. Nivolumab - Wikipedia

    en.wikipedia.org/wiki/Nivolumab

    Nivolumab, sold under the brand name Opdivo, is an anti-cancer medication used to treat a number of types of cancer. [2] This includes melanoma, lung cancer, malignant pleural mesothelioma, renal cell carcinoma, Hodgkin lymphoma, head and neck cancer, urothelial carcinoma, colon cancer, esophageal squamous cell carcinoma, liver cancer, gastric cancer, and esophageal or gastroesophageal ...

  7. Moderna jumps as vaccine shows benefit in head and neck ...

    www.aol.com/news/moderna-jumps-personalized...

    Data from 22 patients who received the vaccine, mRNA-4157, in combination with Keytruda was reported at the American Association for Cancer Research Annual Meeting at San Diego on Monday.

  8. Checkpoint inhibitor - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor

    The deletion of CISH in effector T cells has been shown to dramatically augment TCR signaling and subsequent effector cytokine release, proliferation and survival. The adoptive transfer of tumor-specific effector T cells knocked out or knocked down for CISH resulted in a significant increase in functional avidity and long-term tumor immunity.

  9. Merck posts better-than-expected results on Keytruda ... - AOL

    www.aol.com/news/merck-posts-better-expected...

    Keytruda sales rose 21% to $6.6 billion as the company was able to increase use of the drug in earlier stage cancers, topping analyst forecasts of $6.5 billion. For the full year, Keytruda ...

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