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  2. Active site - Wikipedia

    en.wikipedia.org/wiki/Active_site

    The active site consists of amino acid residues that form temporary bonds with the substrate, the binding site, and residues that catalyse a reaction of that substrate, the catalytic site. Although the active site occupies only ~10–20% of the volume of an enzyme, [ 1 ] : 19 it is the most important part as it directly catalyzes the chemical ...

  3. Biological roles of the elements - Wikipedia

    en.wikipedia.org/wiki/Biological_roles_of_the...

    In these, a normally nonessential element can treat a disease (often a micronutrient deficiency). An example is fluorine, which reduces the effects of iron deficiency in rats. Some of the benign elements are radioactive. As such they alter life due to their potential to cause mutations. This effect could be interpreted as either adverse or ...

  4. Enzyme - Wikipedia

    en.wikipedia.org/wiki/Enzyme

    The catalytic site and binding site together compose the enzyme's active site. The remaining majority of the enzyme structure serves to maintain the precise orientation and dynamics of the active site. [30] In some enzymes, no amino acids are directly involved in catalysis; instead, the enzyme contains sites to bind and orient catalytic ...

  5. Zymogen - Wikipedia

    en.wikipedia.org/wiki/Zymogen

    In biochemistry, a zymogen (/ ˈ z aɪ m ə dʒ ən,-m oʊ-/ [1] [2]), also called a proenzyme (/ ˌ p r oʊ ˈ ɛ n z aɪ m / [3] [4]), is an inactive precursor of an enzyme.A zymogen requires a biochemical change (such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site) for it to become an active enzyme.

  6. Competitive inhibition - Wikipedia

    en.wikipedia.org/wiki/Competitive_inhibition

    The active site is a region on an enzyme to which a particular protein or substrate can bind. The active site will thus only allow one of the two complexes to bind to the site, either allowing a reaction to occur or yielding it. In competitive inhibition, the inhibitor resembles the substrate, taking its place and binding to the active site of ...

  7. ATP synthase - Wikipedia

    en.wikipedia.org/wiki/ATP_synthase

    In the "loose" state, ADP and phosphate enter the active site; in the adjacent diagram, this is shown in pink. The enzyme then undergoes a change in shape and forces these molecules together, with the active site in the resulting "tight" state (shown in red) binding the newly produced ATP molecule with very high affinity. Finally, the active ...

  8. Endocytosis - Wikipedia

    en.wikipedia.org/wiki/Endocytosis

    The different types of endocytosis. Endocytosis is a cellular process in which substances are brought into the cell. The material to be internalized is surrounded by an area of cell membrane, which then buds off inside the cell to form a vesicle containing the ingested materials.

  9. Actin - Wikipedia

    en.wikipedia.org/wiki/Actin

    Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils.It is found in essentially all eukaryotic cells, where it may be present at a concentration of over 100 μM; its mass is roughly 42 kDa, with a diameter of 4 to 7 nm.