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Central pain syndrome, also known as central neuropathic pain, [1] is a neurological condition consisting of constant moderate to severe pain due to damage to the central nervous system (CNS) which causes a sensitization of the pain system. [2] [3] The extent of pain and the areas affected are related to the cause of the injury. [4]
Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
Jaw pain Stress and grinding your teeth at night are both generally benign reasons behind why your jaw may be aching. But persistent jaw pain may also be a sign of an underlying health condition.
Up to 7–8% of the European population is affected by neuropathic pain, [4] and in 5% of persons it may be severe. [5] [6] The pain may result from disorders of the peripheral nervous system or the central nervous system (brain and spinal cord). Neuropathic pain may occur in isolation or in combination with other forms of pain.
The pain is either localized to the injured region, referred to a dermatomal region, or innervation territory of the nerves in the area. [20] Chronic pain after burns injury; Chronic whiplash injury associated pain; Chronic pain after musculoskeletal injury; Chronic pain after peripheral nerve injury or chronic pain after central nervous system ...
It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia. [3] [1] PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days ...
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