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The reaction is the result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol, and is caused by an aldehyde dehydrogenase 2 deficiency. [4] This syndrome has been associated with lower than average rates of alcoholism, possibly due to its association with adverse effects after drinking alcohol. [5]
Includes bibliographical references Basic issues. Developmental aspects of aging, alcohol involvement, and their interrelationship / Robert A. Zucker -- Methodological issues in survey research with older Americans / A. Regula Herzog -- Drinking in an older population : cross-sectional and longitudinal data from the Australian Twin Registry / Kathleen K. Bucholz ...
[7] [8] [9] Severe pain after drinking alcohol may indicate a more serious underlying condition. [ 5 ] [ 10 ] Drinking alcohol in addition to consuming calcium cyanamide can cause permanent or long-lasting intolerance (nitrolime disease), [ 11 ] [ 12 ] contributing (in conjunction with other substances) to the accumulation of harmful ...
[4] [8] As of 2001, there were an estimated 26.8 million children of alcoholics (COAs) in the United States, with as many as 11 million of them under the age of 18. [9] Children of addicts have an increased suicide rate and on average have total health care costs 32 percent greater than children of nonalcoholic families. [9] [10]
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...
Rhinophyma develops in certain individuals with an unknown predisposition from long-standing rosacea which has progressed to a severe form. [2]Although rhinophyma has been commonly presumed to be linked to alcoholism, a direct causal relationship between the condition and excessive alcohol consumption has not been substantiated. [2]
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [1] [2] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [3] [4] use).
In addition to respiratory failure and accidents caused by its effects on the central nervous system, alcohol causes significant metabolic derangements. Hypoglycaemia occurs due to ethanol's inhibition of gluconeogenesis, especially in children, and may cause lactic acidosis, ketoacidosis, and acute kidney injury. Metabolic acidosis is ...