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Esthesioneuroblastoma is a rare cancer of the nasal cavity. Arising from the upper nasal tract, esthesioneuroblastoma is believed to originate from sensory neuroepithelial cells , also known as neuroectodermal olfactory cells.
Neuroblastoma is the most common cancer in babies and the third-most common cancer in children after leukemia and brain cancer. [5] About one in every 7,000 children is affected at some time. [2] About 90% of cases occur in children less than 5 years old, and it is rare in adults. [2] [3] Of cancer deaths in children, about 15% are due to ...
8590 18317 Ensembl ENSG00000184933 ENSMUSG00000070417 UniProt O95222 n/a RefSeq (mRNA) NM_003696 NM_010983 RefSeq (protein) NP_003687 n/a Location (UCSC) Chr 11: 6.79 – 6.8 Mb Chr 7: 106.59 – 106.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Olfactory receptor 6A2 is a protein that in humans is encoded by the OR6A2 gene. It is Class II (tetrapod -specific) olfactory receptor ...
Neuroblastoma is a rare form of a malignant cancer which can start in the olfactory nerve, which is responsible for smell sensation. This cancer can become aggressive and progress into the ethmoid sinuses, brain cavity, surrounds the cribriform plate.
Targeted molecular therapy for neuroblastoma involves treatment aimed at molecular targets that have a unique expression in this form of cancer. Neuroblastoma, the second most common pediatric malignant tumor, often involves treatment through intensive chemotherapy. A number of molecular targets have been identified for the treatment of high ...
Even with aggressive therapy, stage IV neuroblastoma carries a poor prognosis, with a three-year survival rate of 30–40%. [7] Compared with other types of cancer, neuroblastoma is rare. Scientific advances have allowed the development of individualized treatments, with techniques such as immunotherapy being targeted to specific kinds of ...
The degree of differentiation of neuroblastoma is correlated to the prognosis, with a wide variety of outcomes (from tumor regression to recurrence and mortality). The standard of care is the use of chemotherapy, surgical resection and radiation, although most aggressive neuroblastomas have demonstrated to be resistant to these therapies.
Pseudorosettes are present in neuroblastoma, medulloblastoma, malignant melanoma, ependymoma, Merkel cell carcinoma, neuroendocrine tumor of the skin, seborrheic keratosis, dendritic cell neurofibroma, astroblastoma, large cell neuroendocrine tumor of the cervix, clear cell ependymoma of the spinal cord, celiac disease, nasal tumor of olfactory ...
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