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  2. Chromosome 18 - Wikipedia

    en.wikipedia.org/wiki/Chromosome_18

    Chromosome 18 pair in human male karyogram. Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells .

  3. Trinucleotide repeat containing 18 - Wikipedia

    en.wikipedia.org/wiki/Trinucleotide_repeat...

    According to the UCSC Genome Browser, TNRC18 is located within Chromosome 7 in humans (chr7: 5,306,800-5,423,546). There are 29 introns and 30 exons listed. Directly preceding TNRC18 is SLC29A4 and immediately following is AC092171.4. [8] SLC29A4 encodes the plasma membrane monoamine transporter in humans.

  4. SMC protein - Wikipedia

    en.wikipedia.org/wiki/SMC_protein

    The SMC proteins have the potential to form a larger ring-like structure. The ability to create different architectural arrangements allows for various regulations of functions. Some of the possible configurations are double rings, filaments, and rosettes. Double rings are 4 SMC proteins bound at the heads and hinge, forming a ring.

  5. Integrin beta 2 - Wikipedia

    en.wikipedia.org/wiki/Integrin_beta_2

    Integrin beta 2. In molecular biology, CD18 ( Integrin beta chain-2) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. [ 5] Upon binding with one of a number of alpha chains, CD18 is capable of forming multiple heterodimers, which play significant roles in cellular adhesion and cell surface signaling, as well as ...

  6. Chromosome - Wikipedia

    en.wikipedia.org/wiki/Chromosome

    A chromosome is a package of DNA with part or all of the genetic material of an organism. In most chromosomes, the very long thin DNA fibers are coated with nucleosome -forming packaging proteins; in eukaryotic cells the most important of these proteins are the histones. These proteins, aided by chaperone proteins, bind to and condense the DNA ...

  7. NPC1 - Wikipedia

    en.wikipedia.org/wiki/NPC1

    NPC1 gene is located on the long (q) arm of chromosome 18 at position 11.2. Niemann-Pick disease, type C1 ( NPC1) is a membrane protein that mediates intracellular cholesterol trafficking in mammals. In humans the protein is encoded by the NPC1 gene (chromosome location 18q11). [5] [6]

  8. Mothers against decapentaplegic homolog 4 - Wikipedia

    en.wikipedia.org/wiki/Mothers_against...

    In mammals, SMAD4 is coded by a gene located on chromosome 18. In humans, the SMAD4 gene contains 54 829 base pairs and is located from pair n° 51,030,212 to pair 51,085,041 in the region 21.1 of the chromosome 18. Pattern of the chromosome 18 in Homo sapiens. The SMAD 4 gene is located on the long arm of the chromosome, at locus 21.1. This ...

  9. Kinetochore - Wikipedia

    en.wikipedia.org/wiki/Kinetochore

    Kinetochore. A kinetochore ( / kɪˈnɛtəkɔːr /, /- ˈniːtəkɔːr /) is a disc-shaped protein structure associated with duplicated chromatids in eukaryotic cells where the spindle fibers attach during cell division to pull sister chromatids apart. [1] The kinetochore assembles on the centromere and links the chromosome to microtubule ...