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Chromosome 18 pair in human male karyogram. Chromosome 18 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 18 spans about 80 million base pairs (the building material of DNA) and represents about 2.5 percent of the total DNA in cells .
In genetics, chromosome translocation is a phenomenon that results in unusual rearrangement of chromosomes. This includes balanced and unbalanced translocation, with two main types: reciprocal, and Robertsonian translocation. Reciprocal translocation is a chromosome abnormality caused by exchange of parts between non-homologous chromosomes.
H&E stain. A synovial sarcoma (also known as malignant synovioma [1]) is a rare form of cancer which occurs primarily in the extremities of the arms or legs, often in proximity to joint capsules and tendon sheaths. [2] It is a type of soft-tissue sarcoma . The name "synovial sarcoma" was coined early in the 20th century, as some researchers ...
The Philadelphia chromosome or Philadelphia translocation ( Ph) is a specific genetic abnormality in chromosome 22 of leukemia cancer cells (particularly chronic myeloid leukemia (CML) cells). This chromosome is defective and unusually short because of reciprocal translocation, t (9;22) (q34;q11), of genetic material between chromosome 9 and ...
Bcl-2. Bcl-2, encoded in humans by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins. BCL2 blocks programmed cell death ( apoptosis) [5] while other BCL2 family members can either inhibit or induce it. [6] [7] It was the first apoptosis regulator identified in any organism. [8]
Trisomy 18 typically results in life-threatening complications for a baby, but one little girl, Georgia, is proof of how one can live with it. Living with trisomy 18: How a 6-year-old girl is ...
Homogeneously staining regions ( HSRs) are chromosomal segments with various lengths and uniform staining intensity after G banding. This type of aberration is also known as Copy Number Gains or Amplification. An HSR is one type of change in a chromosome 's structure which is frequently observed in the nucleus of human cancer cells.
NC_000013 ( FASTA) GenBank. CM000675 ( FASTA) Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 13 spans about 113 million base pairs (the building material of DNA) and represents between 3.5 and 4% of the total DNA in cells .