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Prazosin was a much better tolerated drug than phenoxybenzamine but the problem still remained that it lowered the blood pressure more than desired for a BPH treatment. [ 2 ] [ 8 ] Terazosin was the first long-lasting alpha 1 blocker approved by FDA to treat BPH.
Benign prostatic hyperplasia ( BPH ), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [ 1] Symptoms may include frequent urination, trouble starting to urinate, weak stream, inability to urinate, or loss of bladder control. [ 1] Complications can include urinary tract infections, bladder stones, and ...
Tamsulosin. Tamsulosin, sold under the brand name Flomax among others, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones. [ 6][ 7][ 8] The evidence for benefit with a kidney stone is better when the stone is larger. [ 8] Tamsulosin is taken by mouth.
Alpha blockers work by blocking the effect of nerves in the sympathetic nervous system. This is done by binding to the alpha receptors in smooth muscle or blood vessels. [ 37] α-blockers can bind both reversibly and irreversibly. [ 2] There are several α receptors throughout the body where these drugs can bind.
5α-Reductase inhibitor. Dutasteride, one of the most widely used 5α-reductase inhibitors. 5α-Reductase inhibitors ( 5-ARIs ), also known as dihydrotestosterone ( DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss.
Tadalafil is a widely used medication, mostly prescribed to treat ED and sometimes to treat the symptoms of benign prostatic hyperplasia (BPH) as well as pulmonary arterial hypertension (under the ...
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