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  2. Cyclobenzaprine - Wikipedia

    en.wikipedia.org/wiki/Cyclobenzaprine

    In any case, it is known to inhibit serotonin and norepinephrine reuptake and to block serotonin, adrenergic, histamine, and muscarinic acetylcholine receptors. [6] [7] Chemically, it is very similar to tricyclic antidepressants like amitriptyline. [6] Cyclobenzaprine was approved for medical use in the United States in 1977. [5]

  3. Muscle relaxant - Wikipedia

    en.wikipedia.org/wiki/Muscle_relaxant

    Spasmolytics, also known as "centrally acting" muscle relaxant, are used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions. While both neuromuscular blockers and spasmolytics are often grouped together as muscle relaxant, [ 1 ] [ 2 ] the term is commonly used to refer to spasmolytics only.

  4. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    GHB can also cause absence seizures; [111] [119] [120] the mechanism is currently not known but it is believed to be due to interactions with the GABA B receptor. [119] It is being investigated if endogenous GHB is responsible for non-convulsive seizures in humans. [111] [121] GHB withdrawal is very intense. [122] Physical dependence develops ...

  5. Inside the ‘hostile,’ gun-obsessed homelife of Georgia ...

    www.aol.com/inside-hostile-gun-obsessed-homelife...

    She was also hit with misdemeanors for having “a clear glass pipe used for the ingestion of narcotics,” a baggie containing “multiple” tablets of cyclobenzaprine, a prescription pain pill ...

  6. Benzocycloheptene - Wikipedia

    en.wikipedia.org/wiki/Benzocycloheptene

    Benzocycloheptenes are cycloheptenes with additional benzene rings attached. Most have two benzene rings, and are called dibenzocycloheptenes.. Some benzocycloheptenes and substituted benzocycloheptenes have medical uses as antihistamines, anticholinergics, antidepressants, and antiserotonergics.

  7. Xanomeline - Wikipedia

    en.wikipedia.org/wiki/Xanomeline

    Xanomeline is an agonist that primarily targets the muscarinic acetylcholine receptor family of five muscarinic receptor subtypes, which are designated M 1-M 5. [2] While it binds with near identical affinity to all five of the muscarinic receptor subtypes as measured by displacement of a muscarinic radioligand, the preponderance of evidence suggests that xanomeline acts preferentially in the ...

  8. Clonazepam - Wikipedia

    en.wikipedia.org/wiki/Clonazepam

    The data are also inconclusive on whether benzodiazepines such as clonazepam cause developmental deficits or decreases in IQ in the developing fetus when taken by the mother during pregnancy. Clonazepam, when used late in pregnancy, may result in the development of a severe benzodiazepine withdrawal syndrome in the neonate .

  9. From Liam Payne to Maggie Smith, the stars of music ... - AOL

    www.aol.com/celebrities-died-2024-liam-payne...

    One Direction star Liam Payne, Oscar-winning Harry Potter and ‘Downton Abbey’ actor Maggie Smith and ‘Charmed’ star Shannen Doherty were among the notable figures who died this year

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