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The guaiac test can often be false-positive which is a positive test result when there is in fact no source of bleeding. This is particularly common if the recommended dietary preparation is not followed, as the heme in red meat or the peroxidase or catalase activity in vegetables, especially if uncooked, can cause analytical false positives.
Fecal occult blood testing (FOBT), as its name implies, aims to detect subtle blood loss in the gastrointestinal tract, anywhere from the mouth to the colon.Positive tests ("positive stool") may result from either upper gastrointestinal bleeding or lower gastrointestinal bleeding and warrant further investigation for peptic ulcers or a malignancy (such as colorectal cancer or gastric cancer).
A stool test is a medical diagnostic technique that involves the collection and analysis of fecal matter. Microbial analysis (culturing), microscopy and chemical tests are among the tests performed on stool samples.
The stool guaiac test (or guaiac fecal occult blood test) is conducted to detect the presence of blood in stool that is not apparent to the unaided eye. The main pathogens that are commonly looked for in feces include: Bacteroides species; Salmonella and Shigella; Yersinia tends to be incubated at 30 °C (86 °F), which is cooler than usual
Gum guaicum, or guaiac resin, [2] is a substance produced from the tree species Guaiacum officinale. It is registered as food additive: as a preservative under the E number E241, and as an antioxidant under E314. [3] Guaiac resin is also used medically for the stool guaiac test.
Slide tests are based on orthotolidine (Hematest reagent tablets and Bili-Labstix) or guaiac (Hemoccult and Gastroccult). There is some evidence that orthotolidine-based tests more sensitive than specific, the Hemoccult test's sensitivity reduced by the acidic environment; and the Gastroccult test be the most accurate. [11]
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The invention of the use of Guaiacum for syphilis. The genus is famous as the supplier of lignum vitae, which is the wood of several species in the genus. [citation needed] It is the fourth-hardest variety of wood as measured by the Janka hardness test, requiring a force of 4,500 lb f (20,000 N) to embed a steel ball 0.444 in (1.13 cm) in diameter half that distance into the wood.