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At sufficiently high doses, TCDD has caused cancer in all animals tested. The most sensitive is liver cancer in female rats, and this has long been a basis for risk assessment. [43] Dose-response of TCDD in causing cancer does not seem to be linear, [25] and there is a threshold below
This means that a person living in an average European dwelling with 50 Bq/m 3 has a lifetime excess lung cancer risk of 1.5–3 × 10 −3. Similarly, a person living in a dwelling with a high radon concentration of 1000 Bq/m 3 has a lifetime excess lung cancer risk of 3–6%, implying a doubling of background lung cancer risk. [63]
The site began in 1998 as a pen and paper questionnaire called the Harvard Cancer Risk Index. [2] In January 2000, The Harvard Cancer Risk Index developed into an online assessment and was renamed Your Cancer Risk, and offered assessments for four cancers: breast, colon, lung, and prostate. Six months later, eight additional cancers were added. [3]
Cancer slope factors (CSF) are used to estimate the risk of cancer associated with exposure to a carcinogenic or potentially carcinogenic substance. A slope factor is an upper bound, approximating a 95% confidence limit , on the increased cancer risk from a lifetime exposure to an agent by ingestion or inhalation .
Medical gas therapy is a treatment involving the administration of various gases. It has been used in medicine since the use of oxygen therapy. [1] Most of these gases are drugs, including oxygen. [2] Many other gases, collectively known as factitious airs, were explored for medicinal value in the late eighteenth century. In addition to oxygen ...
Ethyl carbamate has been used as an antineoplastic agent and for other medicinal purposes, but this application ended after it was discovered to be carcinogenic in 1943. . However, Japanese usage in medical injections continued and from 1950 to 1975 an estimated 100 million 2 ml ampules of 7-to-15% solutions of ethyl carbamate were injected into patients as a co-solvent in water for dissolving ...
The corresponding academic peer reviewed article was published in WikiJournal of Medicine and can be cited as: Jouko Tuomisto (2019). Keith Brain; Thomas Shafee (eds.). "Dioxins and dioxin-like compounds: toxicity in humans and animals, sources, and behaviour in the environment" (PDF). WikiJournal of Medicine. 6 (1): 8. doi: 10.15347/WJM/2019.008.
If a fever develops in the neutropenic period, urgent medical assessment is required for neutropenic sepsis, as infections in patients with low neutrophil counts may progress rapidly. Allopurinol is typically co-administered prophylactically to prevent hyperuricemia that results from tumor lysis syndrome, the result of rapid death of tumor cells.