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In follow-up research at the ICR in 1964, Professors Peter Brookes and Philip Lawley proved that chemical carcinogens act by damaging DNA, leading to mutations and the formation of tumours, proving that cancer is a genetic disease based on mutational events. [7] In 1954 the institute was officially renamed The Institute of Cancer Research (ICR).
The Immunologic Constant of Rejection (ICR), is a notion introduced by biologists to group a shared set of genes expressed in tissue destructive-pathogenic conditions like cancer and infection, along a diverse set of physiological circumstances of tissue damage or organ failure, including autoimmune disease or allograft rejection. [1]
Sir Melvyn Francis Greaves (born 12 September 1941) is a British cancer biologist, and Professor of Cell Biology at the Institute of Cancer Research (ICR) in London. [1] He is noted for his research into childhood leukaemia and the roles of evolution in cancer, including important discoveries in the genetics and molecular biology underpinning leukaemia.
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Paul Workman. Workman was born on 30 March 1952 in Workington, Cumbria, England. [2] He was educated at Workington County Grammar School, Cumbria, and completed his BSc degree in Biochemistry at the University of Leicester and his PhD degree in Cancer Pharmacology at the University of Leeds.
Alan Ashworth, FRS (born 1960 in Bolton, Lancashire) is a British molecular biologist, noted for his work on genes involved in cancer susceptibility.He is currently the President of the UCSF Helen Diller Family Comprehensive Cancer Center at the University of California, San Francisco, a multidisciplinary research and clinical care organisation that is one of the largest cancer centres in the ...
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Jonathon Noë Joseph Pines (born 11 October 1961 [4]) is Head of the Cancer Biology Division at the Institute of Cancer Research in London. He was formerly a senior group leader at the Gurdon Institute at the University of Cambridge .