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Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. It is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste. It is a four carbon dimer of ethylene glycol. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. [3] DEG is a widely used solvent. [4]
The following list encompasses notable medicine contamination and adulteration incidents. 1937 Elixir sulfanilamide incident: S. E. Massengill Company used diethylene glycol as the solvent for the antibacterial sulfanilamide, leading to the 1938 passage of the Federal Food, Drug, and Cosmetic Act. [2] [3]
The 1985 Austrian diethylene glycol wine scandal (German: Glykolwein-Skandal) was an incident in which several Austrian wineries illegally adulterated their wines using the toxic substance diethylene glycol (a minor ingredient in some brands of antifreeze) to make the wines taste sweeter and more full-bodied in the style of late harvest wines. [1]
Diethylene glycol can cause acute kidney failure and alongside another related toxin, ethylene glycol, has been linked to the deaths of more than 300 children in Cameroon, Gambia, Indonesia and ...
The Food and Drug Administration has reprimanded at least 28 companies this year, saying they failed to prove sufficient testing of ingredients used in over-the-counter drugs and consumer products ...
The samples were found to have EG contamination of 0.76-100%, according to the WHO. ... South Africa to recall batches of Johnson & Johnson children's cough syrup after Nigeria said it found high ...
The cough syrup in question was produced by Maiden Pharmaceuticals, and it has been implicated in child deaths in Gambia. Tests conducted by two independent laboratories on behalf of the WHO confirmed the presence of lethal toxins—ethylene glycol and diethylene glycol in the syrup. Indian authorities, however, did not find any toxins, but did ...
The batch had 0.25% of diethylene glycol and 2.1% of ethylene glycol, when the acceptable safety limit for both is up to 0.10%, WHO said in its medical product alert. WHO flags India-made syrup in ...