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These effects may include cognitive and behavioral problems, as well as an increased risk of substance use disorders later in life. Current guidelines recommend that opioid use disorder in pregnancy be treated with opioid agonist pharmacotherapy consisting of methadone or buprenorphine to substitute for the drug of abuse. [1]
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual) , in the cheek (buccal) , by injection ( intravenous and subcutaneous ), as a skin patch (transdermal) , or as an implant .
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
These effects may include cognitive and behavioral problems, as well as an increased risk of substance use disorders later in life. Current guidelines recommend that opioid use disorder in pregnancy be treated with opioid agonist pharmacotherapy consisting of methadone or buprenorphine to substitute for the drug of abuse. [153]
Buprenorphine was approved by the United States Food and Drug Administration (FDA) in 2002. [8] The lowest optimal dose of buprenorphine is 8 mg. [8] Buprenorphine has fewer withdrawal symptoms upon discontinuation, lower risk for overdose, and lower potential for abuse; therefore, it is more effective for unsupervised treatment than methadone. [8]
The group found that people taking the GLP-1 medications had a lower risk of a number of health conditions, including Alzheimer’s disease and dementia, addiction, seizures, blood-clotting ...
Those at highest risk of contracting a henipavirus are travelers who are exposed to infected animals (primarily bats and pigs) or who eat foods contaminated by those animals’ body fluids, per ...
Buprenorphine appears to be associated with more favorable outcomes compared to methadone for treating opioid use disorder (OUD) in pregnancy. Studies show that buprenorphine is linked to lower risks of preterm birth, greater birth weight, and larger head circumference without increased harm. [ 155 ]