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Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [1] Complications may include seizures, cerebral palsy, or kernicterus. [1] In most of cases there is no specific underlying physiologic disorder. [2]
Several important factors that may predispose late-preterm infants to medical conditions associated with immaturity: [1] respiratory distress; apnea; temperature instability; hypoglycemia; hyperbilirubinemia; poor feeding; At 34–35 weeks, the brain weight is only about 2 ⁄ 3 that of a full-term baby. This may lead to an increased risk of ...
If neonatal cholestasis is suspected or an infant is presenting with jaundice after two weeks of life, total and conjugated bilirubin must be measured. [10] Neonatal cholestasis is present if conjugated bilirubin value is >20% of total serum bilirubin or if serum conjugated bilirubin concentration is greater than 1.0 mg/dL. [2]
Bilirubin should be tested from cord blood. [5] Ferritin - because most infants affected by HDN have iron overload, ferritin levels must be measured before giving the infant any additional iron. [11] Newborn Screening Tests - Transfusion with donor blood during pregnancy or shortly after birth can affect the results of the Newborn Screening Tests.
After that, the risk of an IUT is greater than the risk from post birth transfusion. [31] Steroids - Steroids are sometimes given to the mother before IUTs and early delivery to mature the fetal lungs. [31] [32] Phenobarbital - Phenobarbital is sometimes given to the mother to help mature the fetal liver and reduce hyperbilirubinemia. [32] [33]
Jaundice is commonly associated with severity of disease with an incidence of up to 40% of patients requiring intensive care in ICU experiencing jaundice. [48] The causes of jaundice in the intensive care setting is both due to jaundice as the primary reason for ICU stay or as a morbidity to an underlying disease (i.e. sepsis). [48]
More information about potential risk factors that could affect the business and financial results of Natus is included in Natus' annual report on Form 10-K for the year ended December 31, 2011 ...
Hyperbilirubinemia can cause a yellowing of the skin called jaundice depending on the level of bilirubin in the blood. [3] Additional symptoms of hyperbilirubinemia include darker urine ( bilirubinuria ) due to increased unconjugated bilirubin removed from the body in urine.