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  2. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/Hardy–Weinberg_principle

    where n 11, n 12, n 22 are the observed numbers of the three genotypes, AA, Aa, and aa, respectively, and n 1 is the number of A alleles, where = +. An example Using one of the examples from Emigh (1980), [7] we can consider the case where n = 100, and p = 0.34. The possible observed heterozygotes and their exact significance level is given in ...

  3. Genotype frequency - Wikipedia

    en.wikipedia.org/wiki/Genotype_frequency

    if the allele A frequency is denoted by the symbol p and the allele a frequency denoted by q, then p+q=1. For example, if p=0.7, then q must be 0.3. In other words, if the allele frequency of A equals 70%, the remaining 30% of the alleles must be a, because together they equal 100%. [5]

  4. Linkage disequilibrium - Wikipedia

    en.wikipedia.org/wiki/Linkage_disequilibrium

    Robbins [4] showed that recombination is expected to decrease the value of D in each generation by a factor (1 - c), where c is the frequency of recombination. If D between alleles at two loci at generation 0 is given the designation D 0, then in the following generation : D 1 = D 0 (1 - c) and in generation t : D t = D 0 (1 - c) t

  5. Rational root theorem - Wikipedia

    en.wikipedia.org/wiki/Rational_root_theorem

    Moreover, if one sets x = 1 + t, one gets without computation that () = (+) is a polynomial in t with the same first coefficient 3 and constant term 1. [2] The rational root theorem implies thus that a rational root of Q must belong to { ± 1 , ± 1 3 } , {\textstyle \{\pm 1,\pm {\frac {1}{3}}\},} and thus that the rational roots of P satisfy x ...

  6. Quadratic reciprocity - Wikipedia

    en.wikipedia.org/wiki/Quadratic_reciprocity

    Trivially 1 is a quadratic residue for all primes. The question becomes more interesting for −1. Examining the table, we find −1 in rows 5, 13, 17, 29, 37, and 41 but not in rows 3, 7, 11, 19, 23, 31, 43 or 47. The former set of primes are all congruent to 1 modulo 4, and the latter are congruent to 3 modulo 4.

  7. Phosphatidylinositol 4,5-bisphosphate - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylinositol_4,5-b...

    Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P 2, also known simply as PIP 2 or PI(4,5)P 2, is a minor phospholipid component of cell membranes. PtdIns(4,5)P 2 is enriched at the plasma membrane where it is a substrate for a number of important signaling proteins. [1]

  8. Molecular orbital diagram - Wikipedia

    en.wikipedia.org/wiki/Molecular_orbital_diagram

    In agreement with this description the photoelectron spectrum for water shows a sharp peak for the nonbonding 1b 1 MO (12.6 eV) and three broad peaks for the 3a 1 MO (14.7 eV), 1b 2 MO (18.5 eV) and the 2a 1 MO (32.2 eV). [29] The 1b 1 MO is a lone pair, while the 3a 1, 1b 2 and 2a 1 MO's can be localized to give two O−H bonds and an in-plane ...

  9. Quotient space (topology) - Wikipedia

    en.wikipedia.org/wiki/Quotient_space_(topology)

    For example, identifying the ... A map : is a quotient map (sometimes called an identification map [1]) if it is surjective and is equipped with the final topology ...