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XLR-11 (5"-fluoro-UR-144 or 5F-UR-144) is a drug that acts as a potent agonist for the cannabinoid receptors CB 1 and CB 2 with EC 50 values of 98 nM and 83 nM ...
Drug detoxification (informally, detox) is variously construed or interpreted as a type of "medical" intervention or technique in regards to a physical dependence mediated by a drug; as well as the process and experience of a withdrawal syndrome or any of the treatments for acute drug overdose (toxidrome).
Under the United Nations' Single Convention on Narcotic Drugs, cannabis and cannabis resin were traditionally classified under Schedule IV (treaty's most strictly controlled category of drugs [31] [32]) since 1961. However, in 2020, world nations voted to lower the scheduling status of marijuana to the less-restrictive Schedule I.
The Single Convention is the main international treaty related to Cannabis sativa L. and its products.In its Article 1, the Single Convention defines "cannabis" as the "flowering or fruiting tops of the cannabis plant (excluding the seeds and leaves when not accompanied by the tops) from which the resin has not been extracted, by whatever name they may be designated;" while "cannabis resin" is ...
As a result of this regulation, 130 drugs have been withdrawn from the market, but drugs containing multicomponent dextromethorphan can be sold over the counter. [47] In its official press release, the bureau also stated that dextromethorphan is often used as a substitute for marijuana, amphetamine, and heroin by drug abusers, and its use as an ...
Cannabis was commonly sold in tincture form by Parke-Davis, Eli Lilly, E. R. Squibb & Sons, and other drug manufacturers. [10] [11] By the end of the 19th century, the use of cannabis in medicine had declined due to a number of factors, including difficulty in controlling dosages and the rise in popularity of synthetic and opium-derived drugs. [9]
In certain states, providers due to mandatory reporting methods and guidelines inform Child Protective Services of substance abusing parents for Schedule 1 substances including cannabis/marijuana. [79] If a mother tests positive for using the substance during pregnancy in South Carolina she may be required to forfeit her child. [80]
A different 1972 study gave the median lethal dose for intravenous THC in mice and rats at 30–40 mg/kg. [20] A 2020 fact sheet published by the U.S. Drug Enforcement Administration stated that "[n]o deaths from overdose of marijuana have been reported." [21]
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