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2 - Developing follicle 3 - Mature follicle 4 - Ovulation 5 - Corpus luteum 6 - Deterioration of corpus luteum. In biology, folliculogenesis is the maturation of the ovarian follicle, a densely packed shell of somatic cells that contains an immature oocyte.
The follicular phase, also known as the preovulatory phase or proliferative phase, [1] is the phase of the estrous cycle (or, in primates [2] for example, the menstrual cycle) during which follicles in the ovary mature from primary follicle to a fully mature graafian follicle.
Under regulation by gonadotropic hormones, ovarian follicles mature and estrogen secretions exert their biggest influence. The female then exhibits sexually receptive behavior, [12] a situation that may be signaled by visible physiologic changes. Estrus is commonly seen in the mammalian species, including some primates.
An ovarian follicle is a roughly spheroid cellular aggregation set found in the ovaries.It secretes hormones that influence stages of the menstrual cycle.At the time of puberty, women have approximately 200,000 to 300,000 follicles, [1] [2] each with the potential to release an egg cell (ovum) at ovulation for fertilization. [3]
Menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that makes pregnancy possible. The ovarian cycle controls the production and release of eggs and the cyclic release of estrogen and progesterone. The uterine cycle governs the preparation and maintenance of the lining of the ...
The granulosa lutein cells do have aromatase, and use it to produce estrogens, using the androgens previously synthesized by the theca lutein cells, as the granulosa lutein cells in themselves do not have the 17α-hydroxylase or 17,20 lyase to produce androgens. [5] Once the corpus luteum regresses the remnant is known as corpus albicans. [12]
Ovarian follicle activation can be defined as primordial follicles in the ovary moving from a quiescent (inactive) to a growing phase. The primordial follicle in the ovary is what makes up the “pool” of follicles that will be induced to enter growth and developmental changes that change them into pre-ovulatory follicles, ready to be released during ovulation.
Oocytes are then able to mature within the follicle through meiosis. In humans with ovaries, this process occurs continuously, as they are born with a finite number of follicles (between 500,000-1,000,000 follicles), and about 99% of follicles undergo atresia. [4] Only one follicle will be mature enough to release an egg and may be fertilized. [5]