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Acetazolamide is a first generation carbonic anhydrase inhibitor and it decreases the ocular fluid and osmolality in the eye to decrease intraocular pressure. [ 5 ][ 6 ] Common side effects include numbness, ringing in the ears, loss of appetite, vomiting, and sleepiness. [ 2 ]
Acetazolamide is an inhibitor of carbonic anhydrase. It is used for glaucoma, epilepsy (rarely), idiopathic intracranial hypertension, and altitude sickness. For the reduction of intraocular pressure (IOP), acetazolamide inactivates carbonic anhydrase and interferes with the sodium pump, which decreases aqueous humor formation and thus lowers IOP.
Carbonic acid is a chemical compound with the chemical formula H 2 C O 3. The molecule rapidly converts to water and carbon dioxide in the presence of water. However, in the absence of water, it is quite stable at room temperature. [ 5 ][ 6 ] The interconversion of carbon dioxide and carbonic acid is related to the breathing cycle of animals ...
The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO −. 3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper metabolic function. [1] Catalyzed by carbonic anhydrase, carbon dioxide (CO 2 ...
Topiramate selectively inhibits cytosolic (type II) and membrane associated (type IV) forms of carbonic anhydrase. The action on carbonic anhydrase isoenzymes may contribute to the drug's side-effects, including its propensity to cause metabolic acidosis and calcium phosphate kidney stones.
Serious side effects include Steven Johnson syndrome. [3] Those allergic to sulfonamides may be allergic to dorzolamide. [3] [5] Use is not recommended in pregnancy or breastfeeding. [5] It is a carbonic anhydrase inhibitor and works by decreasing the production of aqueous humor. [3] Dorzolamide was approved for medical use in the United States ...
Carbon monoxide poisoningtypically occurs from breathingin carbon monoxide(CO) at excessive levels.[3] Symptoms are often described as "flu-like" and commonly include headache, dizziness, weakness, vomiting, chest pain, and confusion.[1] Large exposures can result in loss of consciousness, arrhythmias, seizures, or death.
Lithium carbonate is an inorganic compound, the lithium salt of carbonic acid with the formula Li 2 CO 3. This white salt is widely used in processing metal oxides. It is on the World Health Organization's List of Essential Medicines [7] for its efficacy in the treatment of mood disorders such as bipolar disorder. [8] [7]