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The main pathophysiology of heart failure is a reduction in the efficiency of the heart muscle, through damage or overloading. As such, it can be caused by a wide number of conditions, including myocardial infarction (in which the heart muscle is starved of oxygen and dies), hypertension (which increases the force of contraction needed to pump blood) and cardiac amyloidosis (in which misfolded ...
High-output heart failure is a heart condition that occurs when the cardiac output is higher than normal because of increased peripheral demand. There is a circulatory overload which may lead to pulmonary edema secondary to an elevated diastolic pressure in the left ventricle .
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]
Alcaide's lab researches interactions between the immune and cardiovascular systems, with particular focuses on cardiac T-cells and the immune response to heart failure. [ 4 ] [ 5 ] One recent project from Alcaide's group examined how T-cell recruitment to the heart following heart failure affected the progression of heart failure pathogenesis.
Circulation is a scientific journal published by Lippincott Williams & Wilkins for the American Heart Association.The journal publishes articles related to research in and the practice of cardiovascular diseases, including observational studies, clinical trials, epidemiology, health services and outcomes studies, and advances in applied (translational) and basic research.
About 12.2 million new strokes are diagnosed each year. One in four stroke survivors will experience another stroke. Stroke survivors are at an increased risk of developing major heart issues ...
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