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Cyanocobalamin is a form of vitamin B 12 used to treat and prevent vitamin B 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
Approximately 50% is stored in the liver, but approximately 0.1% is lost each day, due to secretions into the gut – not all of the vitamin in the gut is reabsorbed. While bile is the main vehicle for B 12 excretion, most of this is recycled via enterohepatic circulation .
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It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. [1] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. [2] From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal–alkyl ...
This historic test consisted, in its first step, of taking an oral dose of radiolabelled vitamin B 12, followed by quantitation of the vitamin in the patient's urine over a 24-hour period via measurement of the radioactivity. A second step of the test repeats the regimen and procedure of the first step, with the addition of oral intrinsic factor.
Anti-vitamins are chemical compounds that inhibit the absorption or actions of vitamins. For example, avidin is a protein in raw egg whites that inhibits the absorption of biotin; it is deactivated by cooking. [50] Pyrithiamine, a synthetic compound, has a molecular structure similar to thiamine, vitamin B 1, and inhibits the enzymes that use ...
Serum concentrations above 50 ng/mL may be cause for concern. Common, most foods do not contain vitamin D, indicating that a deficiency will occur unless people get sunlight exposure or eat manufactured foods purposely fortified with vitamin D. Vitamin D deficiency is a known cause of rickets , and has been linked to numerous other health problems.
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