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Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.
Ibuprofen, an analgesic and non-steroidal anti-inflammatory drug (NSAID), [1] is sold under many brand-names around the world. The most common are Brufen (its earliest registered trademark), Advil, Motrin, and Nurofen .
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The brand first entered the American market in 1984 through Whitehall [3] (itself a division of Wyeth, which was purchased by Pfizer in 2009), [4] the same year ibuprofen gained Food and Drug Administration (FDA) approval for over-the-counter (OTC) sales in the United States (being available via prescription since 1974). [5]
The trust was formed on 1 October 2024 following the merger of Solent NHS Trust and Southern Health NHS Foundation Trust and also incorporates the community and mental health services formerly provided by the Isle of Wight NHS Trust. The merger was approved in November 2023 and was originally planned for April 2024, but was delayed twice. [1] [2]
Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]
An advertisement for Boots from 1911. Boots was established in 1849, by John Boot. [7] After his father's death in 1860, Jesse Boot, aged 10, helped his mother run the family's herbal medicine shop in Nottingham, [8] which was incorporated as Boot and Co. Ltd in 1883, becoming Boots Pure Drug Company Ltd in 1888.
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