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  2. Children in clinical research - Wikipedia

    en.wikipedia.org/wiki/Children_in_clinical_research

    Many drugs work differently in children. Reye's syndrome, for example, is a potentially fatal complication of aspirin therapy in children that is very rare in adults. The 2002 Best Pharmaceuticals for Children Act, allowed the FDA to request National Institutes of Health-sponsored testing for pediatric drug testing, although these requests are ...

  3. Gateway drug effect - Wikipedia

    en.wikipedia.org/wiki/Gateway_drug_effect

    In 2020, the National Institute on Drug Abuse released a research report which supported allegations that marijuana is a "gateway" [3] to more dangerous substance use; one of the peer-reviewed papers cited in the report claims that while "some studies have found that use of legal drugs or cannabis are not a requirement for the progression to ...

  4. Arguments for and against drug prohibition - Wikipedia

    en.wikipedia.org/wiki/Arguments_for_and_against...

    In Europe as of 2007, Sweden spends the second highest percentage of GDP, after the Netherlands, on drug control. [12] The UNODC argues that when Sweden reduced spending on education and rehabilitation in the 1990s in a context of higher youth unemployment and declining GDP growth, illicit drug use rose [13] but restoring expenditure from 2002 again sharply decreased drug use as student ...

  5. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    This study rated alcohol the most harmful drug overall, and the only drug more harmful to others than to the users themselves. [12] 'Drug abuse' is no longer a current medical diagnosis in either of the most used diagnostic tools in the world, the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM ...

  6. Drug prohibition - Wikipedia

    en.wikipedia.org/wiki/Drug_prohibition

    What constitutes a drug varies by century and belief system. What is a psychoactive substance is relatively well known to modern science. [3] Examples include a range from caffeine found in coffee, tea, and chocolate, nicotine in tobacco products; botanical extracts morphine and heroin, and synthetic compounds MDMA and fentanyl.

  7. Drug policy - Wikipedia

    en.wikipedia.org/wiki/Drug_policy

    Under this policy drug use remained low; there was relatively little recreational use and few dependent users, who were prescribed drugs by their doctors as part of their treatment. From 1964 drug use was increasingly criminalised, with the framework still in place as of 2014 largely determined by the 1971 Misuse of Drugs Act.

  8. Drug education - Wikipedia

    en.wikipedia.org/wiki/Drug_education

    Drug education is the planned provision of information, guidelines, resources, and skills relevant to living in a world where psychoactive substances are widely available and commonly used for a variety of both medical and non-medical purposes, some of which may lead to harms such as overdose, injury, infectious disease (such as HIV or hepatitis C), or addiction.

  9. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    Drug addiction, which belongs to the class of substance-related disorders, is a chronic and relapsing brain disorder that features drug seeking and drug abuse, despite their harmful effects. [31] This form of addiction changes brain circuitry such that the brain's reward system is compromised, [ 32 ] causing functional consequences for stress ...