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Tryptophan ball and stick model spinning. Tryptophan (symbol Trp or W) [3] is an α-amino acid that is used in the biosynthesis of proteins.Tryptophan contains an α-amino group, an α-carboxylic acid group, and a side chain indole, making it a polar molecule with a non-polar aromatic beta carbon substituent.
Eosinophilia–myalgia syndrome is a rare, sometimes fatal neurological condition linked to the ingestion of the dietary supplement L-tryptophan. [1] [2] The risk of developing EMS increases with larger doses of tryptophan and increasing age. [3]
^a EINECS for Tryptophan ^a CID 9060 from PubChem ^a CID 6305 from PubChem This page was last edited on 12 April 2023, at 11:38 (UTC). Text is available ...
In enzymology, a tryptophan 2-C-methyltransferase (EC 2.1.1.106) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + L-tryptophan ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + L-2-methyltryptophan
This page was last edited on 25 July 2008, at 18:30 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
As a recreational drug, the effective dosage ranges from 5 to 25 mg. [3] In the 1970s McNeil Laboratories , Inc. was trying to bring 4-methylaminorex to drug market as a sympathomimetic (most commonly used as asthma-medicines), research name was McN-822, they mention that human dose would have been 0.25 mg/kg of body weight.
Aromatic L-amino acid decarboxylase is active as a homodimer. Before addition of the pyridoxal phosphate cofactor, the apoenzyme exists in an open conformation. Upon cofactor binding, a large structural transformation occurs as the subunits pull closer and close the active site. This conformational change results in the active, closed ...
Droxidopa (L-DOPS) is a synthetic precursor or prodrug of norepinephrine used orally in the treatment of certain types of hypotension and other conditions. [ 6 ] [ 7 ] Dipivefrine is a synthetic precursor or prodrug of epinephrine used as an ophthalmic medication .
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