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Baigent C, Blackwell L, Emberson J, et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet ...
According to the AHA, carrying extra weight is linked to higher LDL and lower HDL cholesterol levels. Losing 5% to 10% of your body weight can significantly improve your heart health. If You Smoke ...
There are two kinds of cholesterol. LDL, the “bad” kind, contributes to fatty buildup in your arteries and heart, putting you at risk for heart attacks, while HDL carries the LDL away from ...
Phytosterols are widely recognized as having a proven LDL cholesterol lowering efficacy' [61] A 2018 review found a dose-response relationship for phytosterols, with intakes of 1.5 to 3 g/day lowering LDL-C by 7.5% to 12%, [62] but reviews as of 2017 had found no data indicating that the consumption of phytosterols may reduce the risk of CVD. [63]
After six weeks, The National Cholesterol Education Program recommends checking the LDL cholesterol response to the changes; if the LDL cholesterol goal has not been achieved, other therapeutic options for LDL lowering can be implemented. These include: 2 grams per day of plant stanols or sterols and 10–25 grams per day of soluble fiber.
The Scandinavian Simvastatin Survival Study (also known as the 4S study), was a multicentre, randomized, double-blind, placebo-controlled clinical trial, which provided the initial data that supported the use of the cholesterol-lowering drug, simvastatin, in people with a moderately raised cholesterol and coronary heart disease (CHD); that is people who had previously had a heart attack or angina.
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