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In the "1951 Recommendations" the commission recommended a maximum permissible dose of 0.5 roentgen (0.0044 grays) in any 1 week in the case of whole-body exposure to X and gamma radiation at the surface, and 1.5 roentgen (0.013 grays) in any 1 week in the case of exposure of hands and forearms. [1]
Therapeutic doses of radiation therapy are often given and tolerated well even at higher doses to treat discrete, well-defined anatomical structures. The same dose given over a longer period of time is less likely to cause ARS. Dose thresholds are about 50% higher for dose rates of 20 rad/h, and even higher for lower dose rates. [4]
As of 2012, the risk of low dose radiation in medical imaging was unproven. [7] It is difficult to establish risks associated with low dose radiation. [7] One reason why is that a long period of time occurs from exposure to radiation and the appearance of cancer. [7] Also, there is a natural incidence of cancer. [7]
Recognized effects of higher acute radiation doses are described in more detail in the article on radiation poisoning.Although the International System of Units (SI) defines the sievert (Sv) as the unit of radiation dose equivalent, chronic radiation levels and standards are still often given in units of millirems (mrem), where 1 mrem equals 1/1,000 of a rem and 1 rem equals 0.01 Sv.
The dose values are divided by the maximum dose, referred to as d max, yielding a plot in terms of percentage of the maximum dose. Dose measurements are generally made in water or "water equivalent" plastic with an ionization chamber, since water is very similar to human tissue with regard to radiation scattering and absorption.
The Deep-dose equivalent (DDE) is a measure of external radiation exposure defined by US regulations. It is reported alongside eye and shallow dose equivalents on typical US dosimetry reports. It represents the dose equivalent at a tissue depth of 1 cm (1000 mg/cm2) due to external whole-body exposure to ionizing radiation. [1]
The maximum safe starting doses of different drugs can be obtained from them prior to human clinical trials. [23] Another application is to assess the safe dose for chronic exposure. They are utilized to estimate the daily exposure which does not induce detrimental effects in humans in their lifetime, which is also known as the Reference Dose ...
This means that the radiation dose LD 50 fluctuates with the time at which it is measured. For example, the β radiation dose that causes 50% mortality in the American cockroach at 25 days post-exposure is 5,700 R, but to reach 50% mortality at 3 days post-exposure, 45,610 R are needed.
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