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CimaVax is an active vaccine with which patients are immunized with epidermal growth factor (EGF), thus raising antibodies targeting EGF itself. The EGF is chemically linked to the Neisseria meningitidis outer protein P64k for immunogenicity; [2] Montanide ISA 51 is used as an adjuvant to potentiate the immune response.
A cancer vaccine, or oncovaccine, is a vaccine that either treats existing cancer or prevents development of cancer. [1] Vaccines that treat existing cancer are known as therapeutic cancer vaccines or tumor antigen vaccines .
According to the U.S. Centers for Disease Control and Prevention, while "any vaccine can cause side effects", [11] most side effects are minor, primarily including sore arms or a mild fever. [11] Unlike most medical interventions vaccines are given to healthy people, where the risk of side effects is not as easily outweighed by the benefit of ...
Ongoing lawsuits allege Merck didn’t fully disclose severe and long-term side effects. A condition plaintiffs allege they received from the vaccine is postural orthostatic tachycardia syndrome ...
The program is an outgrowth of the 1986 National Childhood Vaccine Injury Act (NCVIA), which requires health care providers to report: Any event listed by the vaccine manufacturer as a contraindication to subsequent doses of the vaccine. Any event listed in the Reportable Events Table that occurs within the specified time period after vaccination.
The protective effects of the vaccine are expected to last a minimum of 4.5 years after the initial vaccination. [48] While the study period was not long enough for cervical cancer to develop, the prevention of these cervical precancerous lesions (or dysplasias) is believed highly likely to result in the prevention of those cancers. [109]
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When a patient receives multiple vaccines in one visit or a combination vaccine, a VIS should be given for each vaccine or component. The Multi-Vaccine VIS can be used for children receiving DTaP, polio, Hib, hepatitis B, and pneumococcal conjugate vaccines. The Multi-Vaccine VIS is not designed for adults or adolescents. [9] [10]
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