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2. Frovatriptan - Wikipedia

   en.wikipedia.org/wiki/Frovatriptan

   Frovatriptan, sold under the brand name Frova, is a triptan drug developed by Vernalis for the treatment of migraine headaches [1] and for short term prevention of menstrual migraine. [2] The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe.

3. Discovery and development of triptans - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   Sumatriptan [4] binds to 5-HT 1D receptors, zolmitriptan, [5] rizatriptan, [6] naratriptan, [7] almotriptan, [8] and frovatriptan [9] binds to 5-HT 1B/1D and eletriptan [10] binds to 5-HT 1B/1D/1F receptors. Triptans are believed to exert their effects through vasoconstriction, leading to reduced carotid arterial circulation without affecting ...

4. Modified-release dosage - Wikipedia

   en.wikipedia.org/wiki/Modified-release_dosage

   Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1] Sustained-release dosage forms are dosage ...

5. Antimigraine drug - Wikipedia

   en.wikipedia.org/wiki/Antimigraine_drug

   They produce an antimigraine effect by vasoconstriction of the vessels in the brain, as well as inhibiting trigeminal CGRP release and pain transmission. [2] They are normally well tolerated but the vasoconstrictor effects can lead to problematic side effects such as nausea, dizziness and chest discomfort, and therefore require caution in ...

6. Zolmitriptan - Wikipedia

   en.wikipedia.org/wiki/Zolmitriptan

   Zolmitriptan, sold under the brand name Zomig among others, is a serotonergic medication which is used in the acute treatment of migraine attacks with or without aura and cluster headaches. [3] It is taken by mouth as a swallowed or disintegrating tablet or as a nasal spray .

7. Triptan - Wikipedia

   en.wikipedia.org/wiki/Triptan

   Triptans have few side effects if used in correct dosage and frequency. The most common adverse effect is recurrence of migraine. A systematic review found that "rizatriptan 10 mg was the only triptan with a recurrence rate greater than that of placebo". [24]

8. Osmotic-controlled release oral delivery system - Wikipedia

   en.wikipedia.org/wiki/Osmotic-controlled_Release...

   The drug is expelled via the laser-drilled hole visible on the left side of the tablet. The osmotic-controlled release oral delivery system (OROS) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it.

9. Rimegepant - Wikipedia

   en.wikipedia.org/wiki/Rimegepant

   Rimegepant, sold under the brand name Nurtec ODT among others, is a medication used for the acute treatment of migraine with or without aura in adults and the prophylactic/ preventive treatment of episodic migraine in adults.