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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
Polio was eliminated from most parts of the world as part of a decadeslong effort by the World Health Organization and partners to wipe out the disease. Until it is gone from the planet, the virus ...
The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
Itzhak Perlman, a polio survivor, plays the violin while seated. Poliomyelitis (often simply called polio) is an acute viral infection that involves the gastrointestinal tract and occasionally the central nervous system. Poliovirus is acquired by faecal–oral or oral transmission.
For roughly 80 years, she has coped with the aftermath of a polio infection, including the late effects of polio, called post-polio syndrome. She now needs a wheelchair or mobility scooter to get ...
The history of polio (poliomyelitis) infections began during prehistory. Although major polio epidemics were unknown before the 20th century, [1] the disease has caused paralysis and death for much of human history. Over millennia, polio survived quietly as an endemic pathogen until the 1900s when major epidemics began to occur in Europe. [1]
Polio is a debilitating disease that invades the body’s nervous system, and prior to the invention of the polio vaccine, it claimed the lives of hundreds of thousands of people globally every year.