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Cyanoacrylate glue is widely used in human and veterinary medicine. [6] It was in veterinary use for mending bone, hide, and tortoise shell by the early 1970s or before. A cyanoacrylate spray was used in the Vietnam War to reduce bleeding in wounded soldiers until they could be taken to a hospital. [7]
Octyl cyanoacrylate (OCA), a cyanoacrylate ester, is an octyl ester of 2-cyano-2-propenoic acid. It is a clear colorless liquid with a sharp, irritating odor. Its chief use is as the main component of medical cyanoacrylate glues. In medical and veterinary applications, OCA, n-butyl cyanoacrylate (n-BCA) and isobutyl cyanoacrylate (ICA
Methyl cyanoacrylate (MCA; also sometimes referred to as α-cyanoacrylate or alpha-cyanoacrylate) [3] is an organic compound that contains several functional groups: a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues.
Butyl cyanoacrylate has been used to treat arteriovenous malformations [6] by application of the glue into the abnormality through angiography. In gastroenterology, butyl cyanoacrylate is used to treat bleeding gastric varices , which are dilated veins that occur in the setting of liver cirrhosis or thrombosis of the splenic vein . [ 7 ]
2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate . The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips.
Ethyl cyanoacrylate (ECA), a cyanoacrylate ester, is an ethyl ester of 2-cyano-acrylic acid. It is a colorless liquid with low viscosity and a faint sweet smell in pure form. It is the main component of cyanoacrylate glues and can be encountered under many trade names . [ 2 ]
There are three cyanoacrylate compounds currently available as topical skin adhesives. 2-Octyl cyanoacrylate is marketed as Dermabond, SurgiSeal, and more recently LiquiBand Exceed. n-Butyl cyanoacrylate is marketed as Histoacryl, Indermil, GluStitch, GluSeal, PeriAcryl, and LiquiBand. The compound ethyl 2-cyanoacrylate is available as Epiglu. [3]
Animal glue was the most common woodworking glue for thousands of years until the advent of synthetic glues, such as polyvinyl acetate (PVA) and other resin glues, in the 20th century. Today it is used primarily in specialty applications, such as lutherie , pipe organ building , piano repairs, and antique restoration.
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