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The pre-mRNA lacks structures that the messenger RNA (mRNA) requires. First all introns have to be removed from the transcribed RNA through a process known as splicing. Before the RNA is ready for export, a Poly(A)tail is added to the 3' end of the RNA and a 5' cap is added to the 5' end.
This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and the ribosome creates the ...
RNA splicing is a process in molecular biology where a newly-made precursor messenger RNA (pre-mRNA) transcript is transformed into a mature messenger RNA ().It works by removing all the introns (non-coding regions of RNA) and splicing back together exons (coding regions).
In eukaryotic cells, once precursor mRNA (pre-mRNA) has been transcribed from DNA, it is processed to mature mRNA. This removes its introns —non-coding sections of the pre-mRNA. The mRNA is then exported from the nucleus to the cytoplasm , where it is bound to ribosomes and translated into its corresponding protein form with the help of tRNA .
Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. In virology, the term transcription is used when referring to mRNA synthesis from a viral RNA ...
It is important to distinguish the 5' and 3' UTRs from other non-protein-coding RNA. Within the coding sequence of pre-mRNA, there can be found sections of RNA that will not be included in the protein product. These sections of RNA are called introns. The RNA that results from RNA splicing is a sequence of exons. The reason why introns are not ...
soluble RNA - synonym of tRNA: mRNA: messenger RNA - pcRNA protein coding RNA - synonym of mRNA: rRNA: ribosomal RNA multiple families: 5S rRNA: 5S ribosomal RNA RF00001: 5.8S rRNA: 5.8S ribosomal RNA RF00002: SSU rRNA: small subunit ribosomal RNA CL00111: LSU rRNA: large subunit ribosomal RNA CL00112: NoRC RNA: nucleolar remodeling complex ...
The 5′ end is the part of the RNA molecule that is transcribed first, and the 3′ end is transcribed last. The 3′ end is also where the poly(A) tail is found on polyadenylated RNAs. [1] [9] Messenger RNA (mRNA) is RNA that has a coding region that acts as a template for protein synthesis (translation).
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