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In statistics, the Cochran–Mantel–Haenszel test (CMH) is a test used in the analysis of stratified or matched categorical data. It allows an investigator to test the association between a binary predictor or treatment and a binary outcome such as case or control status while taking into account the stratification. [ 1 ]
The test is sometimes called the Mantel–Cox test. The logrank test can also be viewed as a time-stratified Cochran–Mantel–Haenszel test . The test was first proposed by Nathan Mantel and was named the logrank test by Richard and Julian Peto .
Interactive help is available. The program provides methods that are appropriate for matched and independent t-tests, [2] survival analysis, [5] matched [6] and unmatched [7] [8] studies of dichotomous events, the Mantel-Haenszel test, [9] and linear regression. [3]
Cochran-Mantel-Haenszel test allows to test the association between a binary outcome and a binary predictor while taking into account stratification with arbitrary strata size. When its conditions of application are verified, it is identical to the conditional logistic regression score test .
OpenEpi is a free, web-based, open source, operating system-independent series of programs for use in epidemiology, biostatistics, public health, and medicine, providing a number of epidemiologic and statistical tools for summary data.
Other common approaches include the Mantel–Haenszel method [146] and the Peto method. [ 147 ] Seed-based d mapping (formerly signed differential mapping, SDM) is a statistical technique for meta-analyzing studies on differences in brain activity or structure which used neuroimaging techniques such as fMRI, VBM or PET.
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The McNemar's test is a special case of the Cochran–Mantel–Haenszel test; it is equivalent to a CMH test with one stratum for each of the N pairs and, in each stratum, a 2x2 table showing the paired binary responses. [18] Multinomial confidence intervals are used for matched pairs binary data.