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2. Jarisch–Herxheimer reaction - Wikipedia

   en.wikipedia.org/wiki/Jarisch–Herxheimer_reaction

   Lipoproteins released from treatment of Treponema pallidum infections are believed to induce the Jarisch–Herxheimer reaction. [3] The Herxheimer reaction has shown an increase in inflammatory cytokines during the period of exacerbation, including tumor necrosis factor alpha , interleukin-6 and interleukin-8 .

3. 10 Surprising Causes of Back Pain - AOL

   www.aol.com/lifestyle/10-surprising-causes-back...

   Knowing the cause of your back pain is an important first step. While there are many obvious reasons for back pain, there are some that may surprise you. To learn more about causes and treatment ...

4. The Sneaky Sign of Inflammation You Shouldn't Ignore - AOL

   www.aol.com/sneaky-sign-inflammation-shouldnt...

   Back pain. When your back aches and there’s no obvious cause (like lifting heavy boxes or falling), inflammation could be the root cause. Inflammatory back pain tends to come on gradually and ...

5. Spinal disease - Wikipedia

   en.wikipedia.org/wiki/Spinal_disease

   Symptoms for spinal tumors may vary due to factors such as the type of tumor, the region of the spine, and the health of the patient. Back pain is the most common symptom and it can be a problem if the pain is severe, has a time frame that lasts longer than it would for a normal injury, and becomes worse while laying down or at rest.

6. Disc herniation - Wikipedia

   en.wikipedia.org/wiki/Disc_herniation

   After age 50 or 60, osteoarthritic degeneration (spondylosis) or spinal stenosis are more likely causes of low back pain or leg pain. 4.8% of males and 2.5% of females older than 35 experience sciatica during their lifetime. Of all individuals, 60% to 80% experience back pain during their lifetime. In 14%, pain lasts more than two weeks.

7. Unsurprisingly, Women Experience Pain Differently Than Men ...

   www.aol.com/unsurprisingly-women-experience-pain...

   The study, which was published in PNAS Nexus on October 14, may help explain why women are more prone to experience chronic pain and tend to respond less to treatment with opioid medications. Here ...