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Simple diagram of transcription elongation. One strand of the DNA, the template strand (or noncoding strand), is used as a template for RNA synthesis. As transcription proceeds, RNA polymerase traverses the template strand and uses base pairing complementarity with the DNA template to create an RNA copy (which elongates during the traversal).
Eukaryotic Transcription. Eukaryotic transcription is the elaborate process that eukaryotic cells use to copy genetic information stored in DNA into units of transportable complementary RNA replica. [1] Gene transcription occurs in both eukaryotic and prokaryotic cells. Unlike prokaryotic RNA polymerase that initiates the transcription of all ...
An Introduction to Molecular Biology/Transcription of RNA and its modification; Principles of Biochemistry/Cell Metabolism II: RNA transcription; Usage on et.wikipedia.org Transkriptsioon (geneetika) Usage on eu.wikipedia.org Transkripzio (genetika) Usage on fa.wikipedia.org رونویسی (ژنتیک) بیان ژن; Usage on gl.wikipedia.org
Simple cartoon of transcription initiation: 03:08, 10 October 2007: 701 × 203 (28 KB) Forluvoft: Simple cartoon of transcription initiation: 02:42, 10 October 2007:
Primary transcript RNAs are often modified by enzymes after transcription. For example, a poly(A) tail and a 5' cap are added to eukaryotic pre-mRNA and introns are removed by the spliceosome . There are also a number of RNA-dependent RNA polymerases that use RNA as their template for synthesis of a new strand of RNA.
During transcription, RNA polymerase makes a copy of a gene from the DNA to mRNA as needed. This process differs slightly in eukaryotes and prokaryotes. One notable difference is that prokaryotic RNA polymerase associates with DNA-processing enzymes during transcription so that processing can proceed during transcription.
Transcription preinitiation complex, represented by the central cluster of proteins, causes RNA polymerase to bind to target DNA site. The PIC is able to bind both the promoter sequence near the gene to be transcribed and an enhancer sequence in a different part of the genome, allowing enhancer sequences to regulate a gene distant from it.
Transcription is performed by an enzyme called an RNA polymerase, which reads the template strand in the 3' to 5' direction and synthesizes the RNA from 5' to 3'. To initiate transcription, the polymerase first recognizes and binds a promoter region of the gene.