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Bag and contents of a well-known early brand of synthetic cannabinoids named k2 spice that contains herbs covered with synthetic cannabinoids, now illegal throughout much of the world. Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants ...
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
JWH-018, a potent synthetic cannabinoid agonist discovered by John W. Huffman at Clemson University. It was often sold in legal smoke blends collectively known as "spice". Several countries and states have moved to ban it legally. JWH-073; CP-55940, produced in 1974, this synthetic cannabinoid receptor agonist is many times more potent than THC.
Sebastian Zapeta-Calil, accused of burning woman to death on NYC subway, often ‘bugged out’ after smoking K2, shelter roommate says Jack Morphet, Jorge Fitz-Gibbon December 24, 2024 at 10:20 AM
Marketed under the names spice, spike, flamingo, or K2 — this underground drug has become one of the most inexpensive and dangerous ways to get high, reports say. Videos surfacing online have ...
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The NBA and commissioner Adam Silver were eager to make changes to the All-Star Game after last year's contest wasn't very competitive and finished with a final score of 211-186.
Compared with classical cannabinoids, synthetic cannabinoids differ structurally. Some common synthetic cannabinoids are available in the market such as JWH-018, which is the most well-known naphthoylindole and JWH-250, a phenylacetylindole. They are sold under the brand name ”Spice” as a recreational drug over the past decade. [4]
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