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Tyrosinase is a highly conserved protein in animals and apparently arose already in bacteria. The tyrosinase related protein (Tyrp1) and dopachrome tautomerase (Dtc), which encode for protein implicated in melanin synthesis which are the common regulatory elements of exon/intron structure.
22178 Ensembl ENSG00000107165 ENSMUSG00000005994 UniProt P17643 P07147 RefSeq (mRNA) NM_000550 NM_001282014 NM_001282015 NM_031202 RefSeq (protein) NP_000541 NP_001268943 NP_001268944 NP_112479 Location (UCSC) Chr 9: 12.69 – 12.71 Mb Chr 4: 80.75 – 80.77 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Tyrosinase-related protein 1, also known as TYRP1, is an intermembrane enzyme ...
Meaning [1] Latin (or Neo-Latin) origin [1] a.c. before meals: ante cibum a.d., ad, AD right ear auris dextra a.m., am, AM morning: ante meridiem: nocte every night Omne Nocte a.s., as, AS left ear auris sinistra a.u., au, AU both ears together or each ear aures unitas or auris uterque b.d.s, bds, BDS 2 times a day bis die sumendum b.i.d., bid, BID
The tyrosinase (TYR) gene is located on chromosome 11q14. This protein coding gene produces tyrosinase, an enzyme which catalyzes a total of three steps in the conversion of tyrosine to the end product, melanin. [7] This enzyme and conversion process takes place within melanocytes, which are specialized cells for melanin production. [8]
An example of such a protein is the enzyme tyrosinase, which is required for melanin production. Normally tyrosinase is produced in minute quantities but its levels are very much elevated in melanoma cells. Oncofetal antigens are another important class of tumor antigens. Examples are alphafetoprotein (AFP) and carcinoembryonic antigen (CEA ...
13190 Ensembl ENSG00000080166 ENSMUSG00000022129 UniProt P40126 P29812 RefSeq (mRNA) NM_001129889 NM_001922 NM_001322182 NM_001322183 NM_001322184 NM_001322185 NM_001322186 NM_010024 RefSeq (protein) NP_001123361 NP_001309111 NP_001309112 NP_001309113 NP_001309114 NP_001309115 NP_001913 NP_034154 Location (UCSC) Chr 13: 94.44 – 94.48 Mb Chr 14: 118.25 – 118.29 Mb PubMed search Wikidata ...
In the context of skin, “kojic acid blocks the production of tyrosinase, which is critical for the formation of melanin, the pigment molecule in the skin,” says Carmen Castilla, M.D., a board ...
Meaning Origin language and etymology Example(s) -iasis: condition, formation, or presence of Latin -iasis, pathological condition or process; from Greek ἴασις (íasis), cure, repair, mend mydriasis: iatr(o)-of or pertaining to medicine or a physician (uncommon as a prefix but common as a suffix; see -iatry)