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  2. Sequence homology - Wikipedia

    en.wikipedia.org/wiki/Sequence_homology

    Two segments of DNA can have shared ancestry because of three phenomena: either a speciation event (orthologs), or a duplication event (paralogs), or else a horizontal (or lateral) gene transfer event (xenologs). [1] Homology among DNA, RNA, or proteins is typically inferred from their nucleotide or amino acid sequence similarity. Significant ...

  3. Homology (biology) - Wikipedia

    en.wikipedia.org/wiki/Homology_(biology)

    Two segments of DNA can have shared ancestry because of either a speciation event or a duplication event . Homology among proteins or DNA is typically inferred from their sequence similarity. Significant similarity is strong evidence that two sequences are related by divergent evolution of a common ancestor.

  4. Low copy repeats - Wikipedia

    en.wikipedia.org/wiki/Low_copy_repeats

    The two widely accepted methods for SD detection [7] are: 1. Whole-genome assembly comparison (WGAC), in which regions of homology within the assembly are identified. 2. Whole-genome shotgun sequence detection (WSSD), in which the duplication of regions is inferred by increased read coverage at the site of segmental duplication.

  5. Bivalent (genetics) - Wikipedia

    en.wikipedia.org/wiki/Bivalent_(genetics)

    The search for the homologous target, helped by numerous proteins collectively referred as the synaptonemal complex, cause the two homologs to pair, between the leptotene and the pachytene phases of meiosis I. [4] Resolution of the DNA recombination intermediate into a crossover exchanges DNA segments between the two homologous chromosomes at a ...

  6. Homologous recombination - Wikipedia

    en.wikipedia.org/wiki/Homologous_recombination

    This produces two single-stranded (ss) DNA tails and one ss loop. The loop and tails enlarge as RecBCD moves along the DNA. Step 3: The two tails anneal to produce a second ss DNA loop, and both loops move and grow. Step 4: Upon reaching the Chi hotspot sequence (5' GCTGGTGG 3'; red dot) RecBCD nicks the 3’-ended strand.

  7. Holliday junction - Wikipedia

    en.wikipedia.org/wiki/Holliday_junction

    The two pathways for homologous recombination in eukaryotes, showing the formation and resolution of Holliday junctions. The Holliday junction is a key intermediate in homologous recombination, a biological process that increases genetic diversity by shifting genes between two chromosomes, as well as site-specific recombination events involving integrases.

  8. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  9. Science project - Wikipedia

    en.wikipedia.org/wiki/Science_project

    A science project is an educational activity for students involving experiments or construction of models in one of the science disciplines. Students may present their science project at a science fair, so they may also call it a science fair project. Science projects may be classified into four main types.