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Causes of edema that are generalized to the whole body can cause edema in multiple organs and peripherally. For example, severe heart failure can cause pulmonary edema, pleural effusions, ascites and peripheral edema. Such severe systemic edema is called anasarca. In rare cases, a parvovirus B19 infection may cause generalized edemas. [9]
Peripheral edema is edema (accumulation of fluid causing swelling) in tissues perfused by the peripheral vascular system, usually in the lower limbs. In the most dependent parts of the body (those hanging distally ), it may be called dependent edema.
When symptoms grow worse (more on this later), heart failure can cause swelling in the ankles and legs, ... weeping of fluid, inability to walk, fever, pain, increased shortness of breath, ...
Patients present with an acute onset of swelling, pain, erythema, prominent tenderness, warmness and limited range of motion in both ankles. [1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension.
Lymphedema, also known as lymphoedema and lymphatic edema, is a condition of localized swelling caused by a compromised lymphatic system. [2] The lymphatic system functions as a critical portion of the body's immune system and returns interstitial fluid to the bloodstream .
Causes [2] of venous stasis include: Obesity; Pregnancy; Previous damage to leg; Blood clot; Smoking; Swelling and inflammation of a vein close to the skin; Congestive heart failure. [3] Long periods of immobility that can be encountered from driving, [4] flying, bed rest/hospitalization, or having an orthopedic cast.
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