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The hair follicle is an organ found in mammalian skin. [1] It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. [1]
Huxley's layer is the second layer of the inner root sheath of the hair and consists of one or two layers of horny, flattened, nucleated cells. It lies between Henle's layer and the cuticle . [ 1 ]
The inner root sheath or internal root sheath of the hair follicle is located between the outer root sheath and the hair shaft. [1] It is made of three layers: Henle's layer, Huxley's layer, and the cuticle. [2] The inner root sheaf serves to protect growing hair. [3]
a delicate cuticle next the hair, composed of a single layer of imbricated scales with atrophied nuclei; Huxley's layer; Henle's layer; The term "trichilemmal" refers to the outer root sheath. [2] The IRS functions to mould, adhere, as well as participate in the keratinization of growing hair. [3]
The base of a hair's root (the "bulb") contains the cells that produce the hair shaft. [12] Other structures of the hair follicle include the oil producing sebaceous gland which lubricates the hair and the arrector pili muscles, which are responsible for causing hairs to stand up.
Diagram of the hair shaft, indicating medulla (innermost), cortex, and cuticle (exterior.) Anatomy of hair. The cortex of the hair shaft is located between the hair cuticle and medulla and is the thickest hair layer. It contains most of the hair's pigment, giving the hair its color. The major pigment in the cortex is melanin, which is also ...
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In mammalian outer hair cells, the varying receptor potential is converted to active vibrations of the cell body. This mechanical response to electrical signals is termed somatic electromotility; [13] it drives variations in the cell's length, synchronized to the incoming sound signal, and provides mechanical amplification by feedback to the traveling wave.