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Mometasone furoate was patented in 1981 and came into medical use in 1987. [14] It is on the World Health Organization's List of Essential Medicines [15] and is available as a generic medication. [16] [17] In 2022, it was the 311th most commonly prescribed medication in the United States, with more than 200,000 prescriptions. [18]
Topical steroids are the topical forms of corticosteroids.Topical steroids are the most commonly prescribed topical medications for the treatment of rash and eczema.Topical steroids have anti-inflammatory properties and are classified based on their skin vasoconstrictive abilities. [1]
Mometasone/formoterol, sold under the brand name Dulera among others, is a fixed-dose combination medication used in the long-term treatment of asthma. [1] It contains mometasone a steroid and formoterol a long-acting beta agonist. [1] It is only recommended in those for whom an inhaled steroid is not sufficient. [1] It is used by inhalation. [1]
It is the first asthma triple-combination therapy; it consists of a fixed-dose combination of three active substances (indacaterol, glycopyrronium bromide and mometasone furoate) in capsules, to be administered using an inhaler. [11] An optional electronic sensor may also be co-packed with the product. [11]
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2-Furoyl chloride is an acyl chloride of furan.It takes the form of a corrosive liquid, which is more irritating to the eyes than benzoyl chloride. [1] 2-Furoyl chloride is a useful pharmaceutical intermediate and is used in the synthesis of mometasone furoate, an antiinflammatory prodrug used in the treatment of skin disorders, hay fever and asthma.
The methasones (or metasones) are a class of corticosteroids [1] which are generally used in dermatology.They are defined by substitution with a methyl group at the C16α or C16β position of the pregnane steroid nucleus.
[1] [2] [3] It contains olopatadine hydrochloride and mometasone furoate monohydrate. [1] [2] It is sprayed into the nose. [1] [2] Common side effects include an unpleasant taste . [1] It was approved for medical use in Australia in December 2019, [1] [4] and in the United States in January 2022. [2]