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2. Gene therapy for osteoarthritis - Wikipedia

   en.wikipedia.org/.../Gene_therapy_for_osteoarthritis

   Unlike pharmacological treatments which are administered locally or systemically as a series of interventions, gene therapy aims to establish sustained therapeutic effect after a single, local injection. [1] The main risk factors for osteoarthritis are age [2] [3] and body mass index, [4] [3] as such, OA is predominantly considered a disease of ...

3. Osteoarthritis - Wikipedia

   en.wikipedia.org/wiki/Osteoarthritis

   Weight loss and exercise provide long-term treatment and are advocated in people with osteoarthritis. [68] Weight loss and exercise are the most safe and effective long-term treatments, in contrast to short-term treatments which usually have risk of long-term harm. [69]

4. Clinical trials on glucosamine and chondroitin - Wikipedia

   en.wikipedia.org/wiki/Clinical_trials_on_glucos...

   The Long-term Evaluation of Glucosamine Sulfate (LEGS) study ran between 2007 and 2011, [61] to study whether glucosamine sulfate, chondroitin sulfate or a combination of both are effective treatments for chronic knee pain due to osteoarthritis. 502 patients (from 605 enrolled) were followed for two years. [62]

5. Knee pain in the US increased 65% over the past 20 years ...

   www.aol.com/help-knees-doing-easy-exercises...

   Osteoarthritis is often the cause of knee pain, especially for women and older adults, according to the Arthritis Foundation. But sore knees may also result from an injury, weak or tight muscles ...

6. Disease-modifying osteoarthritis drug - Wikipedia

   en.wikipedia.org/wiki/Disease-modifying...

   Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have dmoad activity ...

7. Knee cartilage replacement therapy - Wikipedia

   en.wikipedia.org/wiki/Knee_cartilage_replacement...

   Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in extreme cases, bone can be exposed in the joint.