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A V D greater than the total volume of body water (approximately 42 liters in humans [5]) is possible, and would indicate that the drug is highly distributed into tissue. In other words, the volume of distribution is smaller in the drug staying in the plasma than that of a drug that is widely distributed in tissues.
Each organ or tissue can receive different doses of the drug and the drug can remain in the different organs or tissues for a varying amount of time. [1] The distribution of a drug between tissues is dependent on vascular permeability , regional blood flow, cardiac output and perfusion rate of the tissue and the ability of the drug to bind ...
A no-stop limit, also called no decompression limit (NDL) is the theoretical maximum dissolved gas content of each tissue compartment of the whole body, which can be decompressed directly to surface pressure at the chosen ascent rate used by the model, without a need to stop to outgas at any depth, which has an acceptable risk of developing ...
This article contains a list of organs in the human body. It is widely believed that there are 79 organs (this number goes up if you count each bone and muscle as an organ on their own, which is becoming a more common practice [1] [2]); however, there is no universal standard definition of what constitutes an organ, and some tissue groups' status as one is debated. [3]
While bubbles can form anywhere in the body, DCS is most frequently observed in the shoulders, elbows, knees, and ankles. Joint pain ("the bends") accounts for about 60% to 70% of all altitude DCS cases, with the shoulder being the most common site for altitude and bounce diving, and the knees and hip joints for saturation and compressed air ...
Peripherally selective drugs have their primary mechanism of action outside of the central nervous system (CNS), usually because they are excluded from the CNS by the blood–brain barrier. By being excluded from the CNS, drugs may act on the rest of the body without producing side-effects related to their effects on the brain or spinal cord .
The 10,000 steps per day rule isn’t based in science. Here’s what experts have to say about how much you should actually walk per day for maximum benefits.
The following is a list of hormones found in Homo sapiens.Spelling is not uniform for many hormones. For example, current North American and international usage uses [citation needed] estrogen and gonadotropin, while British usage retains the Greek digraph in oestrogen and favours the earlier spelling gonadotrophin.