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Set point theory can be construed as implying weight regulation in a wide or tight range around the set point, in a symmetric or in an asymmetric manner (i.e. treating weight gain and loss either the same or differently), and may apply to regulation of body fat levels specifically (in a multi-compartment model) or to overall body weight.
Set point (endocrinology), a term encompassing a number of quantities (e.g. body weight, body temperature) where the endocrine system contributes to regulation and homeostasis. Setpoint (control system), the target value that an automatic control system, for example PID controller, will aim to reach; Set point theory, a theory describing how ...
[19] [20] The temperature regulator's set point is reset during infections to produce a fever. [17] [21] [22] Organisms are capable of adjusting somewhat to varied conditions such as temperature changes or oxygen levels at altitude, by a process of acclimatisation. Homeostasis does not govern every activity in the body.
The set point assumption is a negative feedback mechanism. [23] Two popular set point theories include the glucostatic set point theory and the lipostatic set point theory. The set point theories of hunger and eating present a number of weaknesses. [24] The current epidemic of obesity and eating disorders undermines these theories. [25]
Two distinct but related processes are considered to be involved in the development of obesity: sustained positive energy balance (energy intake exceeding energy expenditure) and the resetting of the body weight "set point" at an increased value. [106] The second process explains why finding effective obesity treatments has been difficult.
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Allostasis: The process of achieving stability, or homeostasis, through physiological or behavioral change. Autopoiesis : The process by which a system regenerates itself through the self-reproduction of its own elements and of the network of interactions that characterize them.
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