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Migraine (UK: / ˈ m iː ɡ r eɪ n /, US: / ˈ m aɪ-/) [1] [2] is a genetically-influenced complex neurological disorder characterized by episodes of moderate-to-severe headache, most often unilateral and generally associated with nausea and light and sound sensitivity.
Kaycie Kraus, 14, had excruciating migraines and a MRI revealed a brain tumor. Doctors couldn't perform surgery, offered chemotherapy. Laser ablation helped.
Amyloid beta (Aβ) was found to cause neurotoxicity and cell death in the brain when present in high concentrations. Aβ results from a mutation that occurs when protein chains are cut at the wrong locations, resulting in chains of different lengths that are unusable.
Researchers believe migraine attacks begin deep in the brain stem, when communication between nerves is disrupted. These disruptions can signal migraine symptoms, like fatigue and headache, which ...
Newer approaches: C.G.R.P. antibodies, which are once-monthly injections, and Botox injections help block the pathways in the brain that are used during a migraine attack.
It is estimated that 60% of migraine cases are caused by genetics. [1] The role of natural selection in the development of migraines is not known. Fitness-impairing disorders, including migraines, tend to disappear as a result of natural selection, and their frequency decreases to near the rate of spontaneous mutation.
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