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Peptic ulcer disease is when the inner part of the stomach's gastric mucosa (lining of the stomach), the first part of the small intestine, or sometimes the lower esophagus, gets damaged. An ulcer in the stomach is called a gastric ulcer , while one in the first part of the intestines is a duodenal ulcer . [ 1 ]
Ian Hendry (1931—1984, aged 53) died of a stomach haemorrhage in London. Gene Clark (1944–1991, aged 46) had perforated ulcer and died on May 24, 1991. Doug Hepburn (1926–2000, aged 74) had a perforated ulcer and died on November 22, 2000. Philip Agee (1935–2008, aged 72) had a perforated ulcer and died on January 7, 2008.
A peptic ulcer may accompany gastritis. Endoscopic image. Many people with gastritis experience no symptoms at all. However, upper central abdominal pain is the most common symptom; the pain may be dull, vague, burning, aching, gnawing, sore, or sharp. [13]
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Upper gastrointestinal bleeding affects around 50 to 150 people per 100,000 a year. It represents over 50% of cases of gastrointestinal bleeding. [2] A 1995 UK study found an estimated mortality risk of 11% in those admitted to hospital for gastrointestinal bleeding. [3]
Indigestion, also known as dyspepsia or upset stomach, is a condition of impaired digestion. [2] Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. [3] People may also experience feeling full earlier than expected when eating. [4]
Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Since the abdomen contains most of the body's vital organs, it can be an indicator of a wide variety of diseases.
[50] Rauws and Tytgat describe cure of duodenal ulcer by eradication of H. pylori using Borody's triple therapy combination. [51] Triple-therapy, modernized to a proton pump inhibitor and two antibiotics, soon becomes first line therapy for eradication. World Congress of Gastroenterology recommends eradicating H. pylori to cure duodenal ulcers ...