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The BNF for Children developed from the British National Formulary (BNF), which prior to 2005 had provided information on the treatment of children, with the doses largely determined by calculations based on the body weight of the child. The guidance was provided by pharmacists and doctors whose expertise was in the care of adults.
The British National Formulary for Children (BNFC) [1] [19] [20] book, first published September 2005, [2] is published yearly, [2] and details the doses and uses of medicines in children from neonates to adolescents. [1]
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
Artesunate is the first-line treatment for children or adults with severe malaria, [16] [17] [18] usually in combination with another antimalarial drug. There is moderate-quality evidence that treatment with artesunate plus mefloquine is superior to treatment with artesunate plus amodiaquine or artesunate plus sulfadoxine-pyrimethamine. [19]
N-(4-Amino-3-pyridinyl)acetamide or 3-N-acetylamifampridine, the metabolite Amifampridine is quickly and almost completely (93–100%) absorbed from the gut. In a study with 91 healthy subjects, maximum amifampridine concentrations in blood plasma were reached after 0.6 (±0.25) hours when taken without food, or after 1.3 (±0.9) hours after a ...
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
Structural formula for the substance inside Concerta tablet. Following administration of Concerta, plasma concentrations of the l-isomer were approximately 1 / 40 the plasma concentrations of the d-isomer. [77] Note that the substance is the same as for Concerta - the differences lie in other aspects of the individual pills.
[61] [62] The chemical name of imipramine is 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine and its free base form has a chemical formula of C 19 H 24 N 2 with a molecular weight of 280.407 g/mol. [63] The drug is used commercially mostly as the hydrochloride salt; the embonate (pamoate) salt is used for intramuscular ...
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