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Phenylephrine is pregnancy category C. Due to the lack of studies done in animals and in humans, it is not known whether there is harm to the fetus. Phenylephrine should only be given to pregnant women who have a clear need. [51] Extended use may cause rhinitis medicamentosa, a condition of rebound nasal congestion. [52]
However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [12]
The FDA proposed a ban on phenylephrine, a common decongestant found in cold and cough medications. ... “It is the FDA’s role to ensure that drugs are safe and effective,” Patrizia Cavazzoni ...
Oral phenylephrine is used in over-the-counter products like Sudafed and Dayquil to help temporarily relieve the common symptom of colds and allergies. Phenylephrine has been sold for more than 75 ...
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
Phenylephrine is the main ingredient used in many common over-the-counter congestion products. It is safe to use, but an independent advisory committee to the FDA agreed Tuesday that it is ...
Methamphetamine has high brain permeability, [54] whereas phenylephrine and norepinephrine are peripherally selective drugs. [60] [61] The optimal log P for brain permeation and central activity is about 2.1 (range 1.5–2.7). [62] Phenylpropanolamine has been used pharmaceutically exclusively as the hydrochloride salt. [9] [1]
Phenylephrine is found in a wide range of cold and flu medications, including Sudafed PE, Benadryl Allergy D Plus Sinus and Vicks DayQuil Cold and Flu Relief. Here’s what experts say are ...