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  2. Elagolix - Wikipedia

    en.wikipedia.org/wiki/Elagolix

    The medication was approved by the FDA for the treatment of endometriosis-associated pain in the United States on 23 July 2018. [9] [36] It was the first new medication to be approved by the FDA for the treatment of endometriosis in more than a decade.

  3. Relugolix/estradiol/norethisterone acetate - Wikipedia

    en.wikipedia.org/wiki/Relugolix/estradiol/...

    The medication was approved for medical use in the United States in May 2021. [8] [11]In May 2021, the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Ryeqo, intended for the treatment of symptoms of uterine fibroids. [15]

  4. Scientists hunt for potential first new endometriosis drug in ...

    www.aol.com/scientists-hunt-potential-first...

    A new clinical trial has been launched after previous studies showed promise. Scientists hunt for potential first new endometriosis drug in 40 years Skip to main content

  5. Relugolix - Wikipedia

    en.wikipedia.org/wiki/Relugolix

    Relugolix was approved for the treatment of uterine fibroids in Japan in January 2019. [12] [13] It was the second orally active GnRH antagonist to be introduced for medical use, following elagolix (brand name Orilissa) in July 2018. [12] [17] Relugolix was approved for the treatment of prostate cancer in the United States on 18 December 2020 ...

  6. Neurocrine Biosciences - Wikipedia

    en.wikipedia.org/wiki/Neurocrine_Biosciences

    In September 2017, AbbVie submitted a NDA to the FDA for elagolix for the management of endometriosis and associated pain. The submission was supported by two similar Phase 3 clinical studies involving 1,700 women. [27] [28] In October 2017, AbbVie and Neurocrine announced that the FDA granted priority review for the elagolix NDA.

  7. Leuprorelin - Wikipedia

    en.wikipedia.org/wiki/Leuprorelin

    Leuprorelin is in the gonadotropin-releasing hormone (GnRH) analogue family of medications. [10] It works by decreasing gonadotropins and therefore decreasing testosterone and estradiol. [10] Common side effects include hot flashes, unstable mood, trouble sleeping, headaches, and pain at the site of injection. [10]

  8. Endometriosis - Wikipedia

    en.wikipedia.org/wiki/Endometriosis

    Endometriosis is a chronic disease that has direct and indirect costs which include loss of work days, direct costs of treatment, symptom management, and treatment of other associated conditions such as depression or chronic pain. [236]

  9. Gonadotropin-releasing hormone antagonist - Wikipedia

    en.wikipedia.org/wiki/Gonadotropin-releasing...

    [18] [19] [20] When used in fertility treatment they can also be associated with abdominal pain and ovarian hyperstimulation. [ 18 ] [ 20 ] Subcutaneously administered agents are also associated with injection-site reactions [ 19 ] [ 21 ] and abarelix (neither of these being GnRH agonists, but instead being antagonists) has been linked with ...

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