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The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. [1] In the adult, it forms a continuous smooth outer zone with a number of projections ( cortical columns ) that extend down between the pyramids .
Also, the medullary interstitium is highly concentrated (because of the activity of the ascending limb), leading to a strong osmotic gradient from the descending limb to the medulla. Because of these factors, the concentration of the urine increases dramatically in the descending limb.
In other words, a juxtamedullary nephron is a nephron whose renal corpuscle is near the medulla, and whose proximal convoluted tubule and its associated loop of Henle occur deeper in the medulla than the other type of nephron, the cortical nephron. The juxtamedullary nephrons comprise only about 15% of the nephrons in the human kidney.
The renal medulla (Latin: medulla renis 'marrow of the kidney') is the innermost part of the kidney. The renal medulla is split up into a number of sections, known as the renal pyramids. Blood enters into the kidney via the renal artery, which then splits up to form the segmental arteries which then branch to form interlobar arteries.
The functional substance, or parenchyma, of the human kidney is divided into two major structures: the outer renal cortex and the inner renal medulla. Grossly, these structures take the shape of eight to 18 cone-shaped renal lobes, each containing renal cortex surrounding a portion of medulla called a renal pyramid. [18]
The cortex and medulla of the kidney contain nephrons, [21] each of which consists of a glomerulus and a complex tubular system. [22] The cortex contains glomeruli and is responsible for filtering the blood. [7] The medulla is responsible for urine concentration [23] and contains tubules with short and long loops of Henle. [24]
The medulla consists of one or more pyramids, the bases of which start from corticomedullary border. Medulla pyramid with overlying cortex comprises the renal lobe. [28] In multilobar kidneys, the pyramids are separated from each other by dipped into the kidney areas of cortical tissue known as the renal columns. [61]
The kidney is responsible for about half of the total gluconeogenesis in fasting humans. The regulation of glucose production in the kidney is achieved by action of insulin, catecholamines and other hormones. [14] Renal gluconeogenesis takes place in the renal cortex. The renal medulla is incapable of producing glucose due to absence of ...